Two New AChE Inhibitors Isolated from Li Folk Herb Heilaohu “Kadsura coccinea” Stems
نویسندگان
چکیده
منابع مشابه
New Lignans from the Leaves and Stems of Kadsura philippinensis.
Three novel C19 homolignans, taiwankadsurins D (1), E (2) and F (4), and two new C18 lignans kadsuphilins N (3) and O (5) were isolated from the aerial parts of Taiwanese medicinal plant Kadsura philippinensis. The structures of compounds 1-5 were determined by spectroscopic analyses, especially 2D NMR techniques. The structure of compound 5 was further confirmed by X-ray crystallographic analy...
متن کاملAche Inhibitors On
This study tested the hypothesis that repeated exposure to low levels of sarin, pyridostigmine bromide (PB) or their combination, at doses equivalent to those possibly experienced by veterans of the 1991 Persian Gulf War, could lead to persistent or delayed autonomic effects and thus help to explain the cause of clinical findings in this population. Male Sprague-Dawley rats were treated for 3 w...
متن کاملTwo new xanthones from the stems of Cratoxylum cochinchinense.
Two new xanthones, 6-hydroxy-3,7-dimethoxy-8-(3-methylbut-2-enyl)-6',6'-dimethyl-5'-hydroxy-4',5'-dihydropyrano(2',3':1,2)xanthone (1) and 6-hydroxy-3,7-dimethoxy-8-(2-oxo-3-methylbut-3-enyl)-6',6'-dimethyl-5'-hydroxy-4',5'-dihydropyrano(2',3':1,2)xanthone (2), have been isolated from the stems of Cratoxylum cochinchinense (Lour.) Blume. Their structures were established on the basis of spectro...
متن کاملLignans from Kadsura angustifolia.
A new dibenzocyclooctadiene lignan named angustifolin D (1) together with four known lignans: kadsulignan L (2), kadsulignan N (3), schisantherin P (4) and meso-dihydroguaiaretic acid (5) were isolated from the stems of Kadsura angustifolia. Their structures and stereochemistries were elucidated by spectral studies. Compounds 2 and 5 showed moderate platelet-activating factor (PAF) antagonistic...
متن کاملTheoretical Designing of Acetylcholine Esterase (Ache) Inhibitors
Alzheimer’s disease still remains as an untreatable neurological disorder with no successful treatment strategy to prevent or cure or reverse the damage. Globally, AD is 5th major cause of death. Over last three decades, accumulating evidence for Alzheimer’s suggest multiple causes, predominantly the gene make up of affected individuals are altered. Affected individuals suffer from severe loss ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecules
سال: 2019
ISSN: 1420-3049
DOI: 10.3390/molecules24193628